MicroRNA-34a is a tumor suppressor in choriocarcinoma via regulation of Delta-like1

@inproceedings{Pang2012MicroRNA34aIA,
  title={MicroRNA-34a is a tumor suppressor in choriocarcinoma via regulation of Delta-like1},
  author={Ronald T K Pang and Carmen O. N. Leung and Cheuk-Lun Lee and Kevin K.W. Lam and Tianyuan Ye and Philip C. N. Chiu and William Shu Biu Yeung},
  booktitle={BMC Cancer},
  year={2012}
}
Choriocarcinoma is a gestational trophoblastic tumor which causes high mortality if left untreated. MicroRNAs (miRNAs) are small non protein-coding RNAs which inhibit target gene expression. The role of miRNAs in choriocarcinoma, however, is not well understood. In this study, we examined the effect of miR-34a in choriocarcinoma. MiR-34a was either inhibited or ectopically expressed transiently in two choriocarcinoma cell lines (BeWo and JEG-3) respectively. Its actions on cell invasion… CONTINUE READING
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