MicroRNA-34 family expression in bovine gametes and preimplantation embryos

  title={MicroRNA-34 family expression in bovine gametes and preimplantation embryos},
  author={Allison Tscherner and Graham C. Gilchrist and Natasha Smith and Patrick Blondin and Daniel J Gillis and Jonathan Lamarre},
  booktitle={Reproductive biology and endocrinology : RB&E},
BACKGROUND Oocyte fertilization and successful embryo implantation are key events marking the onset of pregnancy. In sexually reproducing organisms, embryogenesis begins with the fusion of two haploid gametes, each of which has undergone progressive stages of maturation. In the final stages of oocyte maturation, minimal transcriptional activity is present and regulation of gene expression occurs primarily at the post-transcriptional level. MicroRNAs (miRNA) are potent effectors of post… CONTINUE READING
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