MicroRNA-31-5p modulates cell cycle by targeting human mutL homolog 1 in human cancer cells

Abstract

MicroRNAs (miRNAs) and DNA mismatch repair (MMR) have been linked to human cancer progression. Human mutL homolog 1 (hMLH1), one of the core MMR genes, defects in lung cancer development. However, the interaction between miRNAs and MMR genes and their regulatory effect on cell cycle remain poorly understood. In this study, we investigated the role of miR-31… (More)
DOI: 10.1007/s13277-013-0741-z

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