MicroRNA-29 family, a crucial therapeutic target for fibrosis diseases.

  title={MicroRNA-29 family, a crucial therapeutic target for fibrosis diseases.},
  author={Yong He and Chen Huang and Xiang Lin and Jun Li},
  volume={95 7},
MicroRNAs (miRNAs) are a class of approximately 20-nucleotides single-stranded endogenous RNAs that regulate gene expression at the post-transcriptional level. miRNAs have recently been known to regulate cell proliferation, differentiation, and apoptosis. Fibrosis is the leading cause of organ dysfunction in diseases and results from an imbalance in the turnover of extracellular matrix components. Accumulating studies have demonstrated that miR-29 family participates in the development of liver… CONTINUE READING


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