MicroRNA-24 regulates cardiac fibrosis after myocardial infarction

  title={MicroRNA-24 regulates cardiac fibrosis after myocardial infarction},
  author={Jue Wang and Weicong Huang and Ruixia Xu and Yu Nie and Xiaoqing Cao and Jiang Meng and Xiuqin Xu and Shengshou Hu and Zhe Zheng},
  booktitle={Journal of cellular and molecular medicine},
Cardiac fibrosis after myocardial infarction (MI) has been identified as a key factor in the development of heart failure. Although dysregulation of microRNA (miRNA) is involved in various pathophysiological processes in the heart, the role of miRNA in fibrosis regulation after MI is not clear. Previously we observed the correlation between fibrosis and the miR-24 expression in hypertrophic hearts, herein we assessed how miR-24 regulates fibrosis after MI. Using qRT-PCR, we showed that miR-24… CONTINUE READING
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