MicroRNA-223 coordinates cholesterol homeostasis.

Abstract

MicroRNAs (miRNAs) regulate a wide variety of biological processes and contribute to metabolic homeostasis. Here, we demonstrate that microRNA-223 (miR-223), an miRNA previously associated with inflammation, also controls multiple mechanisms associated with cholesterol metabolism. miR-223 promoter activity and mature levels were found to be linked to… (More)
DOI: 10.1073/pnas.1215767111

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