MicroRNA-21 promotes osteogenic differentiation by targeting small mothers against decapentaplegic 7.

@article{Li2015MicroRNA21PO,
  title={MicroRNA-21 promotes osteogenic differentiation by targeting small mothers against decapentaplegic 7.},
  author={Hongqiu Li and Feng Yang and Zhe Wang and Q. K. Fu and Aihua Liang},
  journal={Molecular medicine reports},
  year={2015},
  volume={12 1},
  pages={1561-7}
}
Previous studies have suggested that microRNAs (miRNAs/miRs) may positively or negatively control osteogenic differentiation and mineralization by targeting negative regulators of osteogenesis or important osteogenic factors. miR-21 is important in osteoblast differentiation and Smad7 is a critical regulator of osteogenic differentiation, which inhibits proliferation, differentiation and mineralization in mouse osteoblast cells. However, the association between Smad7 and miR-21 remain to be… CONTINUE READING
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