MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance.

@article{Moriyama2009MicroRNA21MB,
  title={MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance.},
  author={Taiki Moriyama and Kenoki Ohuchida and Kazuhiro Mizumoto and Jun Yu and Norihiro Sato and Toshinaga Nabae and Shunichi Takahata and Hiroki Toma and Eishi Nagai and Masao Tanaka},
  journal={Molecular cancer therapeutics},
  year={2009},
  volume={8 5},
  pages={1067-74}
}
Due to the poor prognosis of pancreatic cancer, novel diagnostic modalities for early diagnosis and new therapeutic strategy are urgently needed. Recently, microRNA-21 (miR-21) was reported to be strongly overexpressed in pancreatic cancer as well as in other solid cancers. We investigated the functional roles of miR-21, which have not been fully elucidated in pancreatic cancer. miR-21 expression was assessed in pancreatic cancer cell lines (14 cancer cell lines, primary cultures of normal… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 158 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 37 references

Similar Papers

Loading similar papers…