MicroRNA-21 in peripheral blood mononuclear cells as a novel biomarker in the diagnosis and prognosis of prostate cancer.

@article{Yang2016MicroRNA21IP,
  title={MicroRNA-21 in peripheral blood mononuclear cells as a novel biomarker in the diagnosis and prognosis of prostate cancer.},
  author={Bing Yang and Zheng Liu and Hao Ning and Kai Zhang and Dongliang Pan and Kejia Ding and Wei Huang and Xin-li Kang and Yang Wang and Xiang Chen},
  journal={Cancer biomarkers : section A of Disease markers},
  year={2016},
  volume={17 2},
  pages={
          223-30
        }
}
OBJECTIVE To evaluate the effects of microRNA-21 (miR-21) in peripheral blood mononuclear cells (PBMC) in the diagnosis and prognosis of prostate cancer (PCa). METHODS Proved by pathologic biopsy, 92 patients diagnosed with PCa and also underwent resection operation and 85 patients with benign prostatic hyperplasia (BPH) were selected in this study, as well as 97 healthy volunteers were chosen as the control group. PBMC were extracted to examine the relative expression of miR-21 by real time… CONTINUE READING
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