MicroRNA-204 regulates vascular smooth muscle cell calcification in vitro and in vivo.

@article{Cui2012MicroRNA204RV,
  title={MicroRNA-204 regulates vascular smooth muscle cell calcification in vitro and in vivo.},
  author={Rong-rong Cui and Shi-jun Li and Ling-juan Liu and Lu Yi and Qiu-hua Liang and Xiao Zhu and Guan-Ying Liu and Yuan Liu and Shan-Shan Wu and Xiao-Bo Liao and Ling-Qing Yuan and Ding-an Mao and Er-yuan Liao},
  journal={Cardiovascular research},
  year={2012},
  volume={96 2},
  pages={320-9}
}
AIMS Medial artery calcification is a common macroangiopathy that initiates from a cell-regulated process similar to osteogenesis. Although the mechanisms governing this process remain unclear, epigenomic regulation by specific microRNAs might play a role in vascular smooth muscle cell (VSMC) calcification. In this study, we aimed to investigate whether miR-204 participates in the regulation of VSMC calcification. METHODS AND RESULTS We found that miR-204 was suppressed in mouse aortic VSMCs… CONTINUE READING
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