MicroRNA-203 accelerates apoptosis in LPS-stimulated alveolar epithelial cells by targeting PIK3CA.

@article{Ke2014MicroRNA203AA,
  title={MicroRNA-203 accelerates apoptosis in LPS-stimulated alveolar epithelial cells by targeting PIK3CA.},
  author={X Q Ke and Jie Fang and Xiao-ning Wu and Chen-huan Yu},
  journal={Biochemical and biophysical research communications},
  year={2014},
  volume={450 4},
  pages={1297-303}
}
The pathogenesis of endotoxin-induced acute lung injury (ALI) remains obscure and has not been well elucidated hitherto. Recently, microRNAs have distinct expression profiles in innate immunity, inflammation, and infection. However, the functions of microRNAs in ALI remain unknown. In this study, the functions of microRNAs in the development of ALI were investigated to identify potential drug targets. MicroRNA-203 (miR-203) expression in the lung tissues of lipopolysaccharide (LPS)-challenged… CONTINUE READING

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