MicroRNA-200a inhibits CD133/1+ ovarian cancer stem cells migration and invasion by targeting E-cadherin repressor ZEB2.


OBJECTIVES MicroRNA-200a (miR-200a) has been reported to be a prognostic marker and to play an important role in ovarian cancer progression. The aim of the study was to elucidate the mechanism of miR-200a involved in migration and invasion in CD133/1+ ovarian cancer stem cells (OCSCs). METHODS The expression of miR-200a between CD133/1+ and CD133/1- cells… (More)
DOI: 10.1016/j.ygyno.2011.03.026