MicroRNA-1855 p modulates chemosensitivity of human non-small cell lung cancer to cisplatin via targeting ABCC 1

@inproceedings{Pei2016MicroRNA1855PM,
  title={MicroRNA-1855 p modulates chemosensitivity of human non-small cell lung cancer to cisplatin via targeting ABCC 1},
  author={K Pei and J Zhu and C Wang and Q Xie and J Guo},
  year={2016}
}
Abstract. – OBJECTIVE: MicroRNA-185-5p (miR-185-5p) dysregulation is found in various human cancers. Our purpose is to investigate the association of miR-185-5p expression with the sensitivity of non-small cell lung cancer (NSCLC) to cisplatin. MATERIALS AND METHODS: Real-time PCR or Western blot assay was performed to detect the expression of mature miR-185-5p and ATP-binding cassette, subfamily C, member 1 (ABCC1) protein. Cell lines with abnormal expression of miR-185-5p were generated using… CONTINUE READING

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