MicroRNA-184-mediated inhibition of tumour growth in an orthotopic murine model of neuroblastoma.


BACKGROUND Neuroblastoma is a paediatric cancer which originates from precursor cells of the sympathetic nervous system. Previous studies have shown that miR-184 expression has anti-proliferative effects in neuroblastoma cells grown in culture. Therefore, it was of interest to evaluate this effect in vivo. MATERIALS AND METHODS Neuroblastoma cells… (More)


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