MicroRNA-183 suppresses the vitality, invasion and migration of human osteosarcoma cells by targeting metastasis-associated protein 1.

@article{Sun2018MicroRNA183ST,
  title={MicroRNA-183 suppresses the vitality, invasion and migration of human osteosarcoma cells by targeting metastasis-associated protein 1.},
  author={Xiaoya Sun and Y. Xu and S. Zhang and Xinjie Li and Y. Wang and Y. Zhang and Xuefeng Zhao and Yuebai Li},
  journal={Experimental and therapeutic medicine},
  year={2018},
  volume={15 6},
  pages={
          5058-5064
        }
}
The aim of the present study was to investigate the effects of microRNA (miR)-183 on vitality, invasion, metastasis and apoptosis in osteosarcoma (OS) cells, mediated by its binding to metastasis-associated protein 1 (MTA1). A dual luciferase reporter assay was performed to determine whether MTA1 was a direct target of miR-183. Cell Counting Kit-8, Transwell, scratch-wound healing, fluorescence-activated cell sorting andterminal deoxynucleotidyl transferase dUTP nick end labeling assays were… Expand
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