MicroRNA-182 regulates otocyst-derived cell differentiation and targets T-box1 gene.

  title={MicroRNA-182 regulates otocyst-derived cell differentiation and targets T-box1 gene.},
  author={Xian-Ren Wang and Xuemei Zhang and Jintao Du and Hongyan Jiang},
  journal={Hearing research},
  volume={286 1-2},
BACKGROUND Recently, in vitro and in vivo models have identified that microRNAs (miRNAs), which are extensively expressed in the inner ear, play important roles in inner ear development and function. However, the function of miRNA in vertebrate tissue is not well understood. RESULTS The current study used an in vitro model of embryonic mouse inner ear in a stem/progenitor cell culture to demonstrate that: 1) miR-182 is expressed during differentiation of inner ear stem/progenitor cell into a… CONTINUE READING
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