MicroRNA-181a sensitizes human malignant glioma U87MG cells to radiation by targeting Bcl-2.

@article{Chen2010MicroRNA181aSH,
  title={MicroRNA-181a sensitizes human malignant glioma U87MG cells to radiation by targeting Bcl-2.},
  author={Gong Chen and W. Zhu and De-zhi Shi and Li Lv and Chun Zhang and P. Liu and Weixing Hu},
  journal={Oncology reports},
  year={2010},
  volume={23 4},
  pages={
          997-1003
        }
}
Radiotherapy is widely used in cancer treatment and biological studies. Multiple mechanisms induced by radiation, especially changes of the expression profile of genes, lead to the disruption of cellular homeostasis. MicroRNAs (miRNAs) are important post-transcriptional gene regulators and play an important role in response to cellular stress. Here we investigated the profiles of miRNA expression following exposure to radiation and the possible role of miRNAs in the modulation of… Expand
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