MicroRNA-181a, a potential diagnosis marker, alleviates acute graft versus host disease by regulating IFN-γ production.

@article{Sang2015MicroRNA181aAP,
  title={MicroRNA-181a, a potential diagnosis marker, alleviates acute graft versus host disease by regulating IFN-γ production.},
  author={Wei Sang and Cong Zhang and Dianzheng Zhang and Ying Wang and Cai Sun and Mingshan Niu and Xiaoshen Sun and Cui Zhou and Lingyu Zeng and Bin Pan and Wei Chen and Dongmei Yan and Feng Zhu and Qingyun Wu and Jiang Cao and Kai Zhao and Chong Chen and Zhenyu Li and Depeng Li and Thomas P. Loughran and Kailin Xu},
  journal={American journal of hematology},
  year={2015},
  volume={90 11},
  pages={
          998-1007
        }
}
  • Wei Sang, Cong Zhang, +18 authors Kailin Xu
  • Published in
    American journal of…
    2015
  • Medicine
  • Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a valuable therapeutic strategy for a wide variety of diseases. Acute graft-versus-host disease (aGVHD) is a major complication in up to 75% of allo-HSCT. The absence of a reliable predicative marker for aGVHD onset prevents preemptive treatment and impedes widespread and successful application of this therapy. In this study we found that after allo-HSCT, the levels of miR-181a were reduced significantly prior to the onset of… CONTINUE READING

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