MicroRNA-15b regulates cell cycle progression by targeting cyclins in glioma cells.

@article{Xia2009MicroRNA15bRC,
  title={MicroRNA-15b regulates cell cycle progression by targeting cyclins in glioma cells.},
  author={Hongping Xia and Yanting Qi and Samuel Sai-ming Ng and Xiaona Chen and Shen Chen and Marong Fang and Dan Li and Yu Zhao and Ruiguang Ge and Guo Li and Yang-chao Chen and Ming-liang He and Hsiang-fu Kung and Lihui Lai and Marie C. Lin},
  journal={Biochemical and biophysical research communications},
  year={2009},
  volume={380 2},
  pages={205-10}
}
MicroRNAs (miRNAs) are non-protein-coding RNAs that function as post-transcriptional gene regulators. Recent evidence has shown that miRNA plays a pivotal role in the development of many cancers including glioma, a lethal brain cancer. We have recently compared the miRNA expression profiles between normal brain and glioma tissues from Chinese patients by miRNA microarray and identified a panel of differentially expressed miRNAs. Here, we studied the function of one miRNA, miR-15b, in glioma… CONTINUE READING