MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation.


MicroRNAs (miRNAs) are small noncoding RNAs that regulate vast networks of genes that share miRNA target sequences. To examine the physiologic effects of an individual miRNA-mRNA interaction in vivo, we generated mice that carry a mutation in the putative microRNA-155 (miR-155) binding site in the 3'-untranslated region of activation-induced cytidine… (More)
DOI: 10.1016/j.immuni.2008.04.002


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