MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells.

  title={MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells.},
  author={Maurizio Ceppi and Patr{\'i}cia M Pereira and Isabelle Dunand-Sauthier and Emmanu{\`e}le Barras and Walter Reith and Manuel A. S. Santos and Philippe Pierre},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={106 8},
In response to inflammatory stimulation, dendritic cells (DCs) have a remarkable pattern of differentiation (maturation) that exhibits specific mechanisms to control immunity. Here, we show that in response to Lipopolysaccharides (LPS), several microRNAs (miRNAs) are regulated in human monocyte-derived dendritic cells. Among these miRNAs, miR-155 is highly up-regulated during maturation. Using LNA silencing combined to microarray technology, we have identified the Toll-like receptor/interleukin… CONTINUE READING
Highly Influential
This paper has highly influenced 17 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Highly Cited
This paper has 293 citations. REVIEW CITATIONS


Publications citing this paper.
Showing 1-10 of 171 extracted citations

MicroRNAs: New Regulators of Toll-Like Receptor Signalling Pathways

BioMed research international • 2014
View 7 Excerpts
Highly Influenced

Identification of B cells participated in the mechanism of postmenopausal women osteoporosis using microarray analysis

International journal of clinical and experimental medicine • 2015
View 4 Excerpts
Highly Influenced

Modulation of tolerogenic dendritic cells and autoimmunity.

Seminars in cell & developmental biology • 2015
View 4 Excerpts
Highly Influenced

293 Citations

Citations per Year
Semantic Scholar estimates that this publication has 293 citations based on the available data.

See our FAQ for additional information.


Publications referenced by this paper.
Showing 1-10 of 45 references

Control of protein synthesis and mRNA degradation by microRNAs

J Liu
Curr Opin Cell Biol • 2008
View 2 Excerpts