MicroRNA-146a regulates the maturation process and pro-inflammatory cytokine secretion by targeting CD40L in oxLDL-stimulated dendritic cells.

@article{Chen2011MicroRNA146aRT,
  title={MicroRNA-146a regulates the maturation process and pro-inflammatory cytokine secretion by targeting CD40L in oxLDL-stimulated dendritic cells.},
  author={Ting Chen and Zhoubin Li and Tu Jing and Weiguo Zhu and Junhua Ge and Xiaoye Zheng and Xiaoping Pan and Hui Yan and Jianhua Zhu},
  journal={FEBS letters},
  year={2011},
  volume={585 3},
  pages={
          567-73
        }
}
There is increasing evidence that microRNAs (miRNAs) play important roles in cell proliferation, apoptosis and differentiation that accompany inflammatory responses. However, whether miRNAs are associated with dendritic cell (DC) immuno-inflammatory responses to oxidized low density lipoprotein (oxLDL) stimulation is yet unknown. Our study aims to explore the link of miRNA to lipid-overload and the immuno-inflammatory mechanism for atherosclerosis. Human primary monocyte-derived DCs were… CONTINUE READING
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MicroRNA-146a and human disease.

Scandinavian journal of immunology • 2010
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