MicroRNA-139-5p regulates proliferation of hematopoietic progenitors and is repressed during BCR-ABL-mediated leukemogenesis.

Abstract

MicroRNAs (miRNAs) have emerged as important regulators of the immune system. However, despite this prominence, our understanding of the function of miRNAs in the early hematopoietic stages is incomplete. In this study, we found that miR-139-5p negatively regulated the proliferation of hematopoietic stem cells and progenitor cells and that downregulation of… (More)

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@article{Choi2016MicroRNA1395pRP, title={MicroRNA-139-5p regulates proliferation of hematopoietic progenitors and is repressed during BCR-ABL-mediated leukemogenesis.}, author={Jinwook Choi and Young Kook Kim and Kyungsoo Park and Jinwoo Nah and Sung Soo Yoon and Dong-Wook Kim and Victoria Kim and Rho Hyun Seong}, journal={Blood}, year={2016}, volume={128 17}, pages={2117-2129} }