MicroRNA-133b inhibits hepatocellular carcinoma cell progression by targeting Sirt1.


MicroRNAs (miRNAs) are a class of small non-coding RNAs that function as critical gene regulators by targeting mRNAs for translational repression or degradation. In this study, we showed that the expression level of miR-133b was decreased, while Sirt1 mRNA expression levels were increased in hepatocellular carcinoma (HCC) and cell lines, and we identified… (More)
DOI: 10.1016/j.yexcr.2016.03.027