MicroRNA 132 regulates nutritional stress-induced chemokine production through repression of SirT1.


Human adipose tissue secretes a number of proinflammatory mediators that may contribute to the pathophysiology of obesity-related disorders. Understanding the regulatory pathways that control their production is paramount to developing effective therapeutics to treat these diseases. Using primary human adipose-derived stem cells as a source of preadipocytes… (More)
DOI: 10.1210/me.2009-0117


7 Figures and Tables