MicroRNA-1297 contributes to tumor growth of human breast cancer by targeting PTEN/PI3K/AKT signaling.

@article{Liu2017MicroRNA1297CT,
  title={MicroRNA-1297 contributes to tumor growth of human breast cancer by targeting PTEN/PI3K/AKT signaling.},
  author={Chao Yuan Liu and Zhikui Liu and Xiao Li and Xiaojiang Tang and Jianjun He and Shaoying Lu},
  journal={Oncology reports},
  year={2017},
  volume={38 4},
  pages={
          2435-2443
        }
}
Increasing evidence confirms that aberrant miRNA expression contributes to breast cancer (BC) development and progression. However, the roles of different miRNAs in BC remain to be explored. In the present study, we demonstrated that miR-1297 expression was increased in BC tissues and cell lines. Our clinical analysis revealed that the upregulated miR-1297 expression was significantly correlated with poor prognostic features including advanced TNM stage and larger tumor size. Moreover, we found… CONTINUE READING

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