MicroRNA-125b down-regulation mediates endometrial cancer invasion by targeting ERBB2

@inproceedings{Shang2012MicroRNA125bDM,
  title={MicroRNA-125b down-regulation mediates endometrial cancer invasion by targeting ERBB2},
  author={C. G. Shang and Yan-ming Lu and Li-rong Meng},
  booktitle={Medical science monitor : international medical journal of experimental and clinical research},
  year={2012}
}
BACKGROUND MicroRNAs (miRNAs) are small non-coding nucleotides that regulate mRNA stability and protein expression by imperfect base pairing with the 3'-untranslated region (3'UTR) of target mRNAs. Many miRNAs have been documented to be aberrantly expressed in human cancers, but the role of miRNAs in endometrioid endometrial cancer (EEC) remains poorly understood. The objective of this study was to investigate the effect of miR-125b on EEC development and to explore its molecular mechanism in… CONTINUE READING
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