MicroRNA-122 suppresses cell proliferation and induces cell apoptosis in hepatocellular carcinoma by directly targeting Wnt/β-catenin pathway.

  • Jie Xu, Xiuming Zhu, +4 authors Fusheng Wu
  • Published 2012 in
    Liver international : official journal of the…

Abstract

AIMS To validate whether the anti-cancer effect of microRNA-122 (miR-122) on hepatocellular carcinoma (HCC) is mediated through regulating Wnt/β-catenin signalling pathways. METHODS The expression levels of miR-122 in HCC tissues and varied hepatoma cells were quantified by real-time PCR. MiR-122 agomir was transfected into HepG2, Hep3B cells to over… (More)
DOI: 10.1111/j.1478-3231.2011.02750.x

Cite this paper

@article{Xu2012MicroRNA122SC, title={MicroRNA-122 suppresses cell proliferation and induces cell apoptosis in hepatocellular carcinoma by directly targeting Wnt/β-catenin pathway.}, author={Jie Xu and Xiuming Zhu and Lingjiao Wu and Rong Yang and Zeran Yang and Qiangfeng Wang and Fusheng Wu}, journal={Liver international : official journal of the International Association for the Study of the Liver}, year={2012}, volume={32 5}, pages={752-60} }