MicroRNA-10b induces glioma cell invasion by modulating MMP-14 and uPAR expression via HOXD10.

@article{Sun2011MicroRNA10bIG,
  title={MicroRNA-10b induces glioma cell invasion by modulating MMP-14 and uPAR expression via HOXD10.},
  author={Lihua Sun and Wei Yan and Yingyi Wang and Guan Sun and Hui Luo and Junxia Zhang and Xiefeng Wang and Yongping You and Zhengxiang Yang and Ning Liu},
  journal={Brain research},
  year={2011},
  volume={1389},
  pages={9-18}
}
MicroRNAs are small endogenous noncoding RNAs, which modulate target gene expression by binding with target mRNA sequences in the 3'untranslated region (UTR) with an imperfect complementarity that inhibits the mRNA translation. Many microRNAs have been reported to function as tumor oncogenes or anti-oncogenes. Recently, more and more microRNAs have been reported to contribute to a tumor's invasive potential. Here, we show that microRNA-10b (miR-10b) was over-expressed in glioma samples and… CONTINUE READING
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