MicroRNA-1 regulates smooth muscle cell differentiation by repressing Kruppel-like factor 4.

@article{Xie2011MicroRNA1RS,
  title={MicroRNA-1 regulates smooth muscle cell differentiation by repressing Kruppel-like factor 4.},
  author={Changqing Xie and Huarong Huang and Xuan Sun and Yanhong Guo and Milton Hamblin and Raquel P. Ritchie and Minerva T. Garcia-Barrio and Jifeng Zhang and Yuqing Eugene Chen},
  journal={Stem cells and development},
  year={2011},
  volume={20 2},
  pages={205-10}
}
The role of microRNA-1 (miR-1) has been studied in cardiac and skeletal muscle differentiation. However, it remains unexplored in vascular smooth muscle cells (SMCs) differentiation. The aim of this study was to uncover novel targets of and shed light on the function of miR-1 in the context of embryonic stem cell (ESC) differentiation of SMCs in vitro. miR… CONTINUE READING