MicroRNA: an Emerging Therapeutic Target and Intervention Tool

  title={MicroRNA: an Emerging Therapeutic Target and Intervention Tool},
  author={Zhen Liu and Alhousseynou Sall and Decheng Yang},
  journal={International Journal of Molecular Sciences},
  pages={978 - 999}
MicroRNAs (miRNAs) are a class of short non-coding RNAs with posttranscriptional regulatory functions. To date, more than 600 human miRNAs have been experimentally identified, and estimated to regulate more than one third of cellular messenger RNAs. Accumulating evidence has linked the dysregulated expression patterns of miRNAs to a variety of diseases, such as cancer, neurodegenerative diseases, cardiovascular diseases and viral infections. MiRNAs provide its particular layer of network for… CONTINUE READING