Micro-optical sectioning tomography to obtain a high-resolution atlas of the mouse brain.

Abstract

The neuroanatomical architecture is considered to be the basis for understanding brain function and dysfunction. However, existing imaging tools have limitations for brainwide mapping of neural circuits at a mesoscale level. We developed a micro-optical sectioning tomography (MOST) system that can provide micrometer-scale tomography of a centimeter-sized… (More)
DOI: 10.1126/science.1191776

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