Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation

@article{Lai2002MicroRA,
  title={Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation},
  author={Eric C. Lai},
  journal={Nature Genetics},
  year={2002},
  volume={30},
  pages={363-364}
}
Micro RNAs are a large family of noncoding RNAs of 21–22 nucleotides whose functions are generally unknown. Here a large subset of Drosophila micro RNAs is shown to be perfectly complementary to several classes of sequence motif previously demonstrated to mediate negative post-transcriptional regulation. These findings suggest a more general role for micro RNAs in gene regulation through the formation of RNA duplexes. 
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