Micro-Mechanical Fractional Skin Rejuvenation

@article{Fernandes2013MicroMechanicalFS,
  title={Micro-Mechanical Fractional Skin Rejuvenation},
  author={Justin R. Fernandes and Juan C. Samayoa and G. Felix Broelsch and Michael C. McCormack and Alexa M. Nicholls and Mark A. Randolph and Martin C. Jr. Mihm and William Gerald G. Austen},
  journal={Plastic and Reconstructive Surgery},
  year={2013},
  volume={131},
  pages={216–223}
}
BACKGROUND The most commonly performed skin rejuvenation procedure, laser resurfacing, is associated with adverse events and significant expense. [...] Key Method Photographs were taken and punch biopsies were performed at days 0, 7, 28, 56, and 84. Biopsy specimens were evaluated for histology and collagen content. RESULTS All treatment sites healed quickly, with no evidence of scarring or infection.Expand

Paper Mentions

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References

SHOWING 1-10 OF 44 REFERENCES
Skin Tightening Effect Using Fractional Laser Treatment II: A Pilot Animal Study on Skin Remodeling
TLDR
It is suggested that improvement of the tension in a horizontal direction is essential for skin remodeling and improvement of facial laxity using fractional laser resurfacing. Expand
Percutaneous Collagen Induction: Minimally Invasive Skin Rejuvenation without Risk of Hyperpigmentation—Fact or Fiction?
TLDR
This study evaluated the effect of percutaneous collagen induction therapy on the epidermis, melanocytes, and the pigmentation markers interleukin-10 and melanocyte-stimulating hormone as well as gene expression microarray analysis indicated a faint down-regulation in the MC1R gene both 24 hours and 2 weeks after the procedure. Expand
Percutaneous Collagen Induction Therapy: An Alternative Treatment for Scars, Wrinkles, and Skin Laxity
TLDR
Percutaneous collagen induction was started in 1997 and has proved to be a simple and fast method for safely treating wrinkles and scars and is also suited to regions where laser treatments and deep peels cannot be performed. Expand
Comparison of carbon dioxide laser, erbium:YAG laser, dermabrasion, and dermatome: a study of thermal damage, wound contraction, and wound healing in a live pig model: implications for skin resurfacing.
TLDR
The results show that CO(2) laser resurfacing produces short- and long-term wound contraction that is greater than that induced by purely ablative methods for the same total depth of injury. Expand
The spectrum of laser skin resurfacing: nonablative, fractional, and ablative laser resurfacing.
TLDR
Neither nonablative nor fractional resurfacing produces results comparable to ablative laser skin resurfacing, but both have become much more popular than the latter because the risks of treatment are limited in the face of acceptable improvement. Expand
Histological evaluation of vertical laser channels from ablative fractional resurfacing: an ex vivo pig skin model
TLDR
A standard model is established to document the histological tissue damage profiles after AFR and to test a new laser device at diverse settings to characterize AFR laser channels histologically. Expand
Objective assessment of skin rejuvenation using near-infrared 1064-nm neodymium: YAG laser in Asians
TLDR
The results indicated that NIR irradiation provides safe and effective long-term stimulation of elastin, which is beneficial for improving dilated pores, skin texture, and wrinkles. Expand
Short‐Term Histologic Effects of Nonablative Resurfacing: Results with a Dynamically Cooled Millisecond‐Domain 1320 nm Nd YAG Laser
TLDR
The histologic findings suggest that three passes with fluence and cooling adjusted to a Tmax of 45°C–48°C yields improved clinical results, and the concept of true “nonablative resurfacing” may involve some form of subclinical epidermal injury that improves the clinical outcome. Expand
Clinical improvement following dermabrasion of photoaged skin correlates with synthesis of collagen I.
TLDR
Increase in procollagen I mRNA correlated with clinical improvement, ie, reduction in wrinkling, and this improvement correlates strongly with increased collagen I gene expression. Expand
Immunohistological Evaluation of Skin Responses After Treatment Using a Fractional Ultrapulse Carbon Dioxide Laser on Back Skin
TLDR
Fractional photothermolysis expression and new formation of collagen and elastic fibers lasted as long as 6 months, longer than the previously acknowledged 3 months. Expand
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