Mice with Deletion of Neuromedin B Receptor Exhibit Decreased Oral Glucose-Stimulated Insulin Release.

@article{Paula2016MiceWD,
  title={Mice with Deletion of Neuromedin B Receptor Exhibit Decreased Oral Glucose-Stimulated Insulin Release.},
  author={Gabriela Silva Monteiro Paula and Luana Lopes Souza and Nina O Bressane and R Maravalhas and Marianna Wilieman and Thais Bento-Bernardes and Karina Ribeiro Silva and Leonardo de Souza Mendonça and Karen de Jesus Oliveira and Carmen Cabanelas Pazos-Moura},
  journal={Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme},
  year={2016},
  volume={48 12},
  pages={854-861}
}
Neuromedin B (NB) and gastrin-releasing peptide (GRP) are bombesin-like peptides, found in the gastrointestinal tube and pancreas, among other tissues. Consistent data proposed that GRP stimulates insulin secretion, acting directly in pancreatic cells or in the release of gastrointestinal hormones that are incretins. However, the role of NB remains unclear… CONTINUE READING