Mice lacking synapsin III show abnormalities in explicit memory and conditioned fear.

@article{Porton2010MiceLS,
  title={Mice lacking synapsin III show abnormalities in explicit memory and conditioned fear.},
  author={Barbara Porton and Ramona Marie Rodriguiz and Lindsey E Phillips and John W. Gilbert and Jian Feng and Paul Greengard and H-T Kao and William C. Wetsel},
  journal={Genes, brain, and behavior},
  year={2010},
  volume={9 3},
  pages={257-68}
}
Synapsin III is a neuron-specific phosphoprotein that plays an important role in synaptic transmission and neural development. While synapsin III is abundant in embryonic brain, expression of the protein in adults is reduced and limited primarily to the hippocampus, olfactory bulb and cerebral cortex. Given the specificity of synapsin III to these brain areas and because it plays a role in neurogenesis in the dentate gyrus, we investigated whether it may affect learning and memory processes in… CONTINUE READING