Mibefradil, a T-Type and L-Type Calcium Channel Blocker, Limits Infarct Size through a Glibenclamide-Sensitive Mechanism


Summary. Mibefradil is a novel calcium channel blocker with activity at both L-type and T-type calcium channels. There are data suggesting that this compound can protect the ischemic/reperfused myocardium in spite of the fact that there is a very low abundance of T-type calcium channels within ventricular tissue. The aims of this study were twofold. First… (More)
DOI: 10.1023/A:1007732025184


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