MiRNA-21 promotes fibrosis in orbital fibroblasts from thyroid-associated ophthalmopathy

Abstract

PURPOSE This study aimed to determine the role of miR-21 in orbital fibroblasts obtained from donors with thyroid-associated ophthalmopathy (TAO) and to elucidate the regulation of fibrosis by miR-21 in the pathological process of TAO. METHODS The expression of miR-21 was investigated in orbital tissues from 26 donors with TAO and 10 donors without TAO… (More)

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