MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells

@inproceedings{Matsushima2010MiRNA205MC,
  title={MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells},
  author={Kayoko Matsushima and Hajime Isomoto and Naoyuki Yamaguchi and Naoki Inoue and Haruhisa Machida and Toshiyuki Nakayama and Tomayoshi Hayashi and Masaki Kunizaki and Shigekazu Hidaka and Takeshi Nagayasu and Masahiro Nakashima and Kenta Ujifuku and Norisato Mitsutake and Akira Ohtsuru and Shunichi Yamashita and Manav Korpal and Yibin Kang and Philip A Gregory and Gregory J. Goodall and Shigeru Kohno and Kazuhiko Nakao},
  booktitle={Journal of Translational Medicine},
  year={2010}
}
Esophageal squamous cell carcinoma (ESCC) is often diagnosed at later stages until they are incurable. MicroRNA (miR) is a small, non-coding RNA that negatively regulates gene expression mainly via translational repression. Accumulating evidence indicates that deregulation of miR is associated with human malignancies including ESCC. The aim of this study was to identify miR that could be specifically expressed and exert distinct biological actions in ESCC. Total RNA was extracted from ESCC cell… CONTINUE READING