MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators

@inproceedings{Nilsson2015MiR137IA,
  title={MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators},
  author={Emeli M. Nilsson and Kristian Bruun Laursen and Jonathan Whitchurch and A. S. Mcwilliam and Niels {\O}dum and Jenny Liao Persson and David M Heery and Lorraine J Gudas and Nigel P Mongan},
  booktitle={Oncotarget},
  year={2015}
}
Androgens and the androgen receptor (AR) play crucial roles in male development and the pathogenesis and progression of prostate cancer (PCa). The AR functions as a ligand dependent transcription factor which recruits multiple enzymatically distinct epigenetic coregulators to facilitate transcriptional regulation in response to androgens. Over-expression of AR coregulators is implicated in cancer. We have shown that over-expression of KDM1A, an AR coregulator, contributes to PCa recurrence by… CONTINUE READING

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