MiR-6835 promoted LPS-induced inflammation of HUVECs associated with the interaction between TLR-4 and AdipoR1 in lipid rafts

@inproceedings{Liu2017MiR6835PL,
  title={MiR-6835 promoted LPS-induced inflammation of HUVECs associated with the interaction between TLR-4 and AdipoR1 in lipid rafts},
  author={Jiao Liu and Guang Cun Li and Chuang Qi Chen and Dechang Chen and Qingshan Zhou},
  booktitle={PloS one},
  year={2017}
}
BACKGROUND High mortality rate of critically-ill patients could be induced by sepsis and septic shock, which is the extremely life threatening. The purpose of this work is to identify and evaluate the potential regulatory mechanism of LPS-induced inflammation associated with miR-6835 and lipid rafts in HUVECs. METHODS The 3' UTR luciferase activity of AdipoR1 was detected, which was predicted the potential target gene of miR-6835. Moreover, the treated HUVECs with or without inhibitors or… CONTINUE READING

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