MiR-519d represses ovarian cancer cell proliferation and enhances cisplatin-mediated cytotoxicity in vitro by targeting XIAP

@inproceedings{Pang2014MiR519dRO,
  title={MiR-519d represses ovarian cancer cell proliferation and enhances cisplatin-mediated cytotoxicity in vitro by targeting XIAP},
  author={Yingxin Pang and Hongluan Mao and Liang Shen and Zhe Zhao and Ruihan Liu and Peishu Liu},
  booktitle={OncoTargets and therapy},
  year={2014}
}
BACKGROUND MicroRNAs (miRNAs) are small, noncoding RNAs that are believed to play fundamental roles in tumorigenesis and tumor development at the posttranscriptional level, as negative regulators of gene expression. This study was designed to evaluate the expression and anticancer effect of miR-519d in ovarian cancer. METHODS The expression levels of miR-519d in ovarian cancer cells and tissues were detected by TaqMan quantitative reverse transcriptase-polymerase chain reaction (TaqMan qRT… CONTINUE READING