MiR-449a functions as a tumor suppressor in endometrial cancer by targeting CDC25A.

@article{Ye2014MiR449aFA,
  title={MiR-449a functions as a tumor suppressor in endometrial cancer by targeting CDC25A.},
  author={Wenwei Ye and Jisen Xue and Qian Zhang and Fuyao Li and Wei Zhang and Huijun Chen and Yibo Huang and Feiyun Zheng},
  journal={Oncology reports},
  year={2014},
  volume={32 3},
  pages={1193-9}
}
Accumulating evidence has demonstrated that microRNAs (miRNAs) play critical roles in cancer initiation and development by functioning either as oncogenes or as tumor suppressors. The role of microRNA-449a (miR-449a) in endometrial cancer remains unclear. We examined the levels of miR-449a and miR-449b in benign endometrium, type I and type II endometrial… CONTINUE READING