MiR-376c Down-Regulation Accelerates EGF-Dependent Migration by Targeting GRB2 in the HuCCT1 Human Intrahepatic Cholangiocarcinoma Cell Line

@inproceedings{Iwaki2013MiR376cDA,
  title={MiR-376c Down-Regulation Accelerates EGF-Dependent Migration by Targeting GRB2 in the HuCCT1 Human Intrahepatic Cholangiocarcinoma Cell Line},
  author={Jun Iwaki and Kunio Kikuchi and Yoshiaki Mizuguchi and Yutaka Kawahigashi and Hiroshi Yoshida and Eiji Uchida and Toshihiro Takizawa},
  booktitle={PloS one},
  year={2013}
}
MicroRNA miR-376c was expressed in normal intrahepatic biliary epithelial cells (HIBEpiC), but was significantly suppressed in the HuCCT1 intrahepatic cholangiocarcinoma (ICC) cell line. The biological significance of the down-regulation of miR-376c in HuCCT1 cells is unknown. We hypothesized that miR-376c could function as a tumor suppressor in these cells. To test this hypothesis, we sought the targets of miR-376c, and characterized the effect of its down-regulation on HuCCT1 cells. We… CONTINUE READING
Tweets
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
SHOWING 1-10 OF 24 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 53 REFERENCES

Intrahepatic cholangiocarcinoma

  • Y Nakanuma, MP Curado, S Franceschi, G Gores, V Paradis
  • 2010

Similar Papers

Loading similar papers…