MiR-34a and miR-483-5p are candidate serum biomarkers for adrenocortical tumors.

@article{Patel2013MiR34aAM,
  title={MiR-34a and miR-483-5p are candidate serum biomarkers for adrenocortical tumors.},
  author={Dhaval Patel and Myriem Boufraqech and Meenu Jain and Lisa Zhang and Mei Lin He and Krisana Gesuwan and Neelam Gulati and Naris Nilubol and Tito Fojo and Electron Kebebew},
  journal={Surgery},
  year={2013},
  volume={154 6},
  pages={1224-8; discussion 1229}
}
BACKGROUND Nonfunctioning adrenal incidentalomas are common and many patients undergo adrenalectomy to exclude adrenocortical carcinoma (ACC). Recent studies have shown dysregulated microRNA (miRNA) expression in ACC. The objective of this study was to determine the feasibility and diagnostic accuracy of measuring serum miRNAs in patients with benign and malignant adrenocortical neoplasms. METHOD Five miRNAs were selected from miRNA profiling studies in ACC (miR-let-7d, -34a, -195, -214, and… CONTINUE READING

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