MiR-33a suppresses breast cancer cell proliferation and metastasis by targeting ADAM9 and ROS1

@inproceedings{Zhang2015MiR33aSB,
  title={MiR-33a suppresses breast cancer cell proliferation and metastasis by targeting ADAM9 and ROS1},
  author={Chuankai Zhang and Yunda Zhang and Weiji Ding and Yancheng Lin and Zhengjie Huang and Qi Luo},
  booktitle={Protein & Cell},
  year={2015}
}
MicroRNAs (miRNAs) are small noncoding RNAs that have a pivotal role in the post-transcriptional regulation of gene expression by sequence-specifically targeting multiple mRNAs. Although miR-33a was recently reported to play an important role in lipid homeostasis, atherosclerosis, and hepatic fibrosis, the functions of miR-33a in tumor progression and metastasis are largely unknown. Here, we found that downregulated miR-33a in breast cancer tissues correlates with lymph node metastasis. MiR-33a… CONTINUE READING
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