MiR-339-5p inhibits breast cancer cell migration and invasion in vitro and may be a potential biomarker for breast cancer prognosis

@inproceedings{Wu2010MiR3395pIB,
  title={MiR-339-5p inhibits breast cancer cell migration and invasion in vitro and may be a potential biomarker for breast cancer prognosis},
  author={Zheng-Sheng Wu and Qiang Wu and Chao-qun Wang and Xiao-nan Wang and Yan Wang and Jing-Jing Zhao and Shan-shan Mao and Gui Zhang and Nong Zhang and X{\`i}ao-chun Xu},
  booktitle={BMC Cancer},
  year={2010}
}
MicroRNAs (miRNAs) play an important role in the regulation of cell growth, differentiation, apoptosis, and carcinogenesis. Detection of their expression may lead to identifying novel markers for breast cancer. We profiled miRNA expression in three breast cancer cell lines (MCF-7, MDA-MB-231, and MDA-MB-468) and then focused on one miRNA, miR-339-5p, for its role in regulation of tumor cell growth, migration, and invasion and target gene expression. We then analyzed miR-339-5p expression in… CONTINUE READING

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