MiR-27b directly targets Rab3D to inhibit the malignant phenotype in colorectal cancer

@inproceedings{Luo2018MiR27bDT,
  title={MiR-27b directly targets Rab3D to inhibit the malignant phenotype in colorectal cancer},
  author={Yang Luo and Shi-yong Yu and Jizheng Chen and Jun Qin and Yi-Er Qiu and Ming Zhong and Min Chen},
  booktitle={Oncotarget},
  year={2018}
}
MiRNAs, as oncogenes or as anti-oncogenes, play critically regulated roles in the initiation and progression of colorectal cancer at posttranscriptional level. However, the underlying functions of miR-27b in colorectal cancer remain largely unexplored. Here, we demonstrated miR-27b is significantly down-regulated in colorectal cancer tissues, and decreased miR-27b expression was closely associated with shorter overall survival of patients with colorectal cancer. By gain- and loss-of-function… CONTINUE READING

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