MiR-210--micromanager of the hypoxia pathway.

  title={MiR-210--micromanager of the hypoxia pathway.},
  author={Xin Huang and Quynh-Thu Le and Amato J. Giaccia},
  journal={Trends in molecular medicine},
  volume={16 5},
Hypoxia inducible factors (HIFs) regulate a variety of genes to prepare cells to adapt and survive under a hypoxic environment. Recently, microRNAs (miRNAs) have emerged as a new class of genes regulated by HIFs in response to hypoxia, of which miR-210 is the most consistently and predominantly upregulated miRNA. Functional studies have demonstrated that… CONTINUE READING