MiR-200b is involved in Tgf-β signaling to regulate mammalian palate development

Abstract

Various cellular and molecular events are involved in palatogenesis, including apoptosis, epithelial–mesenchymal transition (EMT), cell proliferation, and cell migration. Smad2 and Snail, which are well-known key mediators of the transforming growth factor beta (Tgf-β) pathway, play a crucial role in the regulation of palate development. Regulatory effects… (More)
DOI: 10.1007/s00418-011-0876-1

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